Every design decision in OVISTA's protocols traces back to a published source. Where the literature is thin, we say so — we don't fill the gap with a guess.
Task timing and structure are grounded in the internationally standardised antisaccade protocol (Antoniades et al., 2013), adapted with published Alzheimer's/MCI-specific evidence where the research calls for it. This is the backbone of how each trial is structured.
Our team conducted a systematic review of the eye-tracking dementia literature — a manuscript currently in peer review — assessing how consistently prior studies report their own methods across 330 verified studies. Basic timing parameters that any protocol depends on are rarely disclosed: response window was documented in only 3% of studies, inter-stimulus interval in under 9%. That audit directly shaped how rigorously OVISTA documents its own protocol parameters, rather than repeating the gaps we found elsewhere.
Published research tells us which oculomotor features matter, and the direction they're expected to move in disease. It does not tell us the exact threshold for an individual patient. Those thresholds come only from OVISTA's own age- and sex-adjusted reference data, gathered specifically for this purpose.
OVISTA is currently in pre-clinical development. Our oculomotor protocols are literature-grounded and undergoing pilot validation; they are not yet cleared as a diagnostic device by any regulatory body. We publish this stage honestly because we think it matters as much as the science itself.
The process behind every task parameter — timing, eccentricity, trial count — follows the same rule.
Every parameter in an OVISTA protocol is either grounded in a specific, citable source, or explicitly flagged as an area where the evidence is currently insufficient. We don't quietly fill a gap with an assumption dressed up as a finding. Where the literature hasn't settled a question yet, our own pilot and normative data collection is designed to help answer it — not to paper over the uncertainty.
OVISTA's research collaborators span cognitive science, clinical psychology, and neurology. We're actively interested in hearing from researchers working on oculomotor biomarkers, early neurodegenerative screening, or normative eye-tracking data.
Interested in oculomotor correlates of attention, inhibition, and executive control.
Interested in early behavioral markers of cognitive decline and validation study design.
Interested in translating oculomotor findings into a usable primary-care referral signal.
If you work in one of these areas and want to talk about OVISTA's evidence base or a potential collaboration, we'd like to hear from you.